Endothelial Function and Oxidative Stress in Cardiovascular Diseases
نویسندگان
چکیده
منابع مشابه
Oxidative Stress and Cardiovascular Diseases
Reactive oxygen species (ROS) are reactive oxygen metabolites resulting from one-electron reduction of oxygen under the influence of a variety of enzymes. In aerobic organisms, they are produced as a byproduct of many cellular metabolic pathways and participate in some processes necessary for the normal life and functioning of the cells, but also in a large number of pathological processes. Oxi...
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MDs (mitochondrial diseases) are a clinically heterogeneous group of disorders characterized by impairment of the respiratory chain function with altered oxidative phosphorylation. We tested the hypothesis that the function of vascular endothelium is affected by increased oxidative stress in MDs. A total of 12 patients with MDs and pair-matched controls were studied. Endothelial function was as...
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Reactive oxygen species (ROS) include a wide variety of molecules and free radicals derived from molecular oxygen. O2 being highly electrophilic can be reduced by one electron at a time producing relatively stable intermediates, such as superoxide anion (O2 ̄), precursor of most ROS and a relevant mediator in many biological reactions. Dismutation of O2 ̄ produces hydrogen peroxide (H2O2), whic...
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Aging-associated cardiovascular diseases (CVDs) have some risk factors that are closely related to oxidative stress. Salvia miltiorrhiza (SM) has been used commonly to treat CVDs for hundreds of years in the Chinese community. We aimed to explore the effects of SM on oxidative stress in aging-associated CVDs. Through literature searches using Medicine, PubMed, EMBASE, Cochrane library, CINAHL, ...
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ژورنال
عنوان ژورنال: Circulation Journal
سال: 2009
ISSN: 1346-9843,1347-4820
DOI: 10.1253/circj.cj-08-1102